In the quest of searching for an answer for Hairloss treatment, we can stumble across anything that means anything. From granny-created recipes like putting red chili-paste on the scalp to highly professional and expensively marketed products that guarantee hair growth. Some are backed with since while others aren't. No matter what the products or practices are hair growth and hair fall are multifactorial. Every individual is unique and the hair problems are unique too. There are gender, age, metabolism, pollution, smoking, personal habits, hygiene, hormones, and even nutrition, they all play an important part in the pattern of hair loss and hair growth. The average hair loss every day can be anywhere from 50-100 hair strands every day without us even noticing. Is that a cause to worry? No, we don't think so. However, if there is excessive hair loss, diffuse hair thinning, breaking, and splitting of the hair then the concern grows. One thing that all trichologists and dermatologists explain to the patients that hair loss and hair growth can also be seasonal and cyclical in phases so they should not worry much if they know how their hair growth and hair loss pattern is. there are several phases like the anagen phase and telogen phase but that is a discussion for another day. Some patients stop washing hair for the fear of losing them and that starts the vicious cycle because if you don't wash the hair regularly it will gather oil dust and a perfect environment for the bacterial playground in addition the blood circulation to the hair follicle will be hampered and then you will see more hair loss. So first thing first " Shampoo Please" Picking up shampoo is another challenge nowadays. for that go with something natural, something mild and with a natural ingredient that you know very well and have heard about it before. Regardless of what we accept or reject there is constant research going on to find Surprisingly, during our data research we came across a wonderful product that most of the world consumes daily. Yes, it's an edible ingredient. Still, couldn't guess it? Exactly you are right, it's Coffee or caffeine. In a recent article "Role of Caffeine in the Management of Androgenetic Alopecia" it was notably mentioned that "Recently, certain newer advances have shown caffeine to have beneficial effects in patients suffering from AGA. The proposed mechanism which would counteract DHT-induced miniaturization of the hair follicle includes inhibition of phosphodiesterase by caffeine, which increases cAMP levels in cells and therefore promotes proliferation by stimulating cell metabolism" Here is another reference "A study conducted by Fischer et al. used a hair organ culture model to investigate the effects of testosterone and caffeine on hair follicle growth stimulation. This in vitro study used scalp biopsy samples from male AGA patients which were cultivated using different concentrations of testosterone and/or caffeine for 120-192 hours. The addition of caffeine in concentrations of 0.001% and 0.005% were found to counteract the suppressive effects of testosterone on hair growth, with a higher hair shaft elongation seen at 120 h after caffeine administration, compared to the control group. This in vitro study thus clearly demonstrates that caffeine is a stimulator of human hair growth which may have importance in the treatment of AGA" Here is one more reference "Regarding the route of delivery of caffeine, hair follicles are considered an important route for drug delivery. A recent study that assessed the follicular penetration of topical caffeine in hair follicles proved hair follicles to be the faster route of drug delivery for topically applied drugs" And finally, just one more reference "An important requirement for the treatment of AGA is follicular drug delivery. A recent study assessed the follicular penetration of caffeine on the topical application in a shampoo formulation for 2 min and showed that penetration via hair follicles was faster and higher compared with the interfollicular route and that hair follicles were the only pathway for faster caffeine absorption during the first 20 min after application" Now, what does all this scientific stuff means? "The beneficial effects of topical application of caffeine in AGA can thus be attributed to inhibition of phosphodiesterase, improvement in barrier function, follicular penetration, stimulation, and promotion of hair growth. Thus, it appears to be a useful adjuvant in the management of AGA." Maybe some of the readers might start wondering what if I just drink coffee from my hair follicles or maybe get my daily dose of caffeine from my caffeine shampoo. We just can't stop you from thinking but we are sure you will only do the right thing. Wash hair with a Caffeine Shampoo and drink coffee from your coffee mug or the cold one with the straw. Get your hair the dose of caffeine they need and enjoy that clean voluminous bouncy hair growth.